The year 2025 has been a rollercoaster for General Hospital fans. Beloved stars have exited, storylines have wrapped, and Port Charles continues to evolve. Here’s a look at the eight biggest departures from the series this year—along with their impact, their ages, and their careers beyond GH.

1. Leslie Charleson (Monica Quartermaine) – Age 79 (1945–2025)

Leslie Charleson was the heart of Port Charles. She played Monica Quartermaine from 1977 until her passing in January 2025. With over 40 years on the show, Monica was central to countless storylines, especially involving the Quartermaine dynasty.

• Other TV roles: As the World Turns, Love Is a Many Splendored Thing, The Wild Wild West, Happy Days, Friends.
• Importance to GH: Monica was the moral compass of the Quartermaines, anchoring their legacy and connecting generations of fans.

2. Chad Duell (Michael Corinthos) – Age 37

Chad Duell joined GH in 2010 as Michael Corinthos and quickly became one of the show’s leading men. After nearly 15 years, he made his final appearance in January 2025.

• Other TV roles: The Suite Life on Deck, The Bay.
• Importance to GH: Michael was a central character, linking the Quartermaine and Corinthos families, making his exit a major shift.

3. Charles Mesure → Chris McKenna (Brennan) — Recast

Charles Mesure exited his role as Brennan in early 2025, with Chris McKenna assuming the role beginning February 4, later being upgraded to contract status in August.

• Other TV roles: The Young and the Restless.
• Importance to GH: His arrival ensures Michael remains in the canvas, but it also closes the book on Duell’s version of the character.

4. Eva LaRue (Natalia Rogers-Ramirez) – Age 58

Eva LaRue, famous for All My Children and CSI: Miami, joined GH in 2024. Her role as Natalia was initially short-term but expanded. Sadly, her character was written off in June 2025 through a tragic overdose storyline.

• Other TV roles: All My Children, CSI: Miami, Full House, Santa Barbara.
• Importance to GH: Natalia brought depth to family-centered plots, even though her time in Port Charles was brief.

5. Jonathan Jackson (Lucky Spencer) – Age 43

Jonathan Jackson, who first joined GH as a teenager in 1993, reprised his iconic role of Lucky Spencer in 2024. By June 2025, he left once again, citing commuting challenges from his home in Tennessee.

• Other TV roles: Nashville, Terminator: The Sarah Connor Chronicles, The Deep End.
• Importance to GH: As the son of Luke and Laura, Lucky is GH royalty. His exits and returns always carry emotional weight.

6. Sofia Mattsson (Sasha Gilmore) – Age 34

Sofia Mattsson exited GH in July 2025 after seven years as Sasha Gilmore. In her final scenes, Sasha left town with her baby daughter Daisy to reconnect with her father, Robert Scorpio.

• Other TV roles: NCIS, StartUp, Two and a Half Men.
• Importance to GH: Sasha’s story of resilience through loss and love touched fans deeply, and her departure was emotional.

7. Kirsten Storms (Maxie Jones) – Age 41

Kirsten Storms has played Maxie since 2005, becoming one of GH’s most beloved heroines. In mid-2025, she announced an extended hiatus after relocating to Tennessee. Nicole Paggi has been brought in temporarily.

• Other TV roles: Zenon: Girl of the 21st Century, Kim Possible (voice), Days of Our Lives.
• Importance to GH: Maxie is a cornerstone character, and Storms’ absence leaves a noticeable gap in storylines.

8. Jeff Kober (Cyrus Renault) – Age 71

Jeff Kober’s menacing portrayal of Cyrus Renault came to an end in February 2025. His exit was storyline-driven, closing out one of GH’s most dangerous villains.

• Other TV roles: China Beach, Sons of Anarchy, The Walking Dead, Law & Order: SVU.
• Importance to GH: Cyrus was one of the most compelling antagonists of recent years, keeping Port Charles on edge.

Why These Exits Matter

This wave of exits and changes has reshaped General Hospital in 2025. Some, like Leslie Charleson’s passing, marked the end of an era. Others, like Kirsten Storms’ hiatus or Rory Gibson’s recast, show how soaps evolve to keep stories alive.

These departures remind fans that while actors may come and go, Port Charles always continues—and the legacy of these characters will forever shape its future.